Assignment: Risk-Benefits Analysis

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Assignment: Risk-Benefits Analysis

Assignment: Risk-Benefits Analysis

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Using the knowledge you gained from the readings, evaluate how a typical drug, when orally administered, may be handled differently by these two patients:

  • Ms. Jones is a 30-year-old female personal trainer that is 5’ 4” tall weighing 110lbs. She regularly drinks socially and sometimes more than a bit when she meets with her bi-weekly book club.
  • Mr. Smith is a 65-year-old software tester who is 6’ tall and weighs 235lbs. He drinks only occasionally.

Assume no other significant medical history or issues with either patient. In your analysis, compare how the two patients will metabolize the drug considering weight, gender, distribution of body water and body fat, age, metabolic state, and alcohol use. Explain how these factors impact the pharmacokinetics of the drug (half-life, dosage, route of administration, and elimination of the drug). Evaluate the impact on the risk-benefits analysis of the use of this drug.

Economic Payoff

Although the normal reason for carrying out a hazards analysis is to improve safety, many companies feel that these analyses provide an economic payback. Unfortunately, such  are hard to verify. The problems to do with trying to determine economic payoff are those associated with all kinds of . If a team identifies a high-consequence hazard that has never actually occurred, and then recommends spending money to make its probability much lower, there is no direct financial benefit to the company. It is difficult to justify spending funds on protecting against what has never actually happened. Other benefits such as the improved understanding of the process that the analysis provides the operators and maintenance workers are even harder to quantif

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